Artificial Intelligence & alien intelligence.
http://www.bbc.com/future/story/20131217-weve-created-alien-intelligence
Of course, other intelligent beings in the universe could have reach a point of creating A.I.
Augmented Human Intelligence.
http://www.bbc.com/future/story/20121218-will-we-ever-have-cyborg-brains
If a persons body is so damaged or crippled, bionic or robotic body parts could improve their quality of life.
Eventually, a persons brain & mind dramatically slows down so simply transplanting their head onto a genetically engineered body or a robotic form still has limitations. Never the less, RoboCop_(2014_film) provides an interesting depiction of a broken man transferred into a robotic suit. Of course, this robotic exoskeleton provides him with tremendous strength & mobility.
In contrast, the Iron_Man_films depict a vehicular spacesuit that the controller can escape from at their convenience.
The big barrier to cross, is to be able to transfer a persons consciousness into a new synthetic form.
http://www.bbc.com/future/story/20121108-will-men-and-machines-merge
Unless a persons consciousness can be successfully transferred, all there will be is a digital copy of the persons mind in the new form. Thus, that new form will only be A.I. in a synthetic body or robotic form. http://en.wikipedia.org/wiki/The_Stepford_Wives_(1975_film)
http://www.bbc.com/future/story/20121121-reading-your-mind
M Kaku http://www.youtube.com/watch?v=L4_ExHIFEjg